We offer research services within:
Pipetting of blood into glass fiber plate manufactured by RefLab
- Chronic spontaneous urticaria (CSU)
- Food allergy, e.g. identification of allergens in genetically modified food items
- Recombinant allergens
- Drug allergy, e.g. monitoring effect of immunotherapy
- Signal transduction in basophils
- Basophil chemotaxis
- Chemokine receptors on basophils
- Autoantibodies for IgE and its receptor
With our unique ex vivo human skin microdialysis model, we can investigate:
Skin microdialysis setup
- Allergic or allergy like adverse effects of drugs (observed or potential)
- Anti-allergic effects of drug candidates
- Drug-induced mast cell and basophil activation
- Pharmacokinetics and drug uptake
- Pharmacodynamics of mast cell stabilizing/anti-allergic drugs
- Administration routes: intradermal injection, intra probe drug delivery or topical
- Mechanisms in allergic-inflammatory reactions (Type I allergy, CSU & autoimmune reactions)
- Biological activity of allergens
Read more about our expertise in the ex vivo skin model here
Please contact us at info@reflab.dk to receive further information.