RefLab is currently involved in R&D projects concerning the following areas:
- Food allergy
- Drug allergy
- Genetically modified food
- Recombinant allergens.
- Signal transduction in basophils
- Basophil chemotaxis
- Chemokine receptors on basophils
- Autoantibodies for IgE and its receptor
- chronic urticarial
In vitro skin microdialysis (SKIM) to detect biomarkers released from different cell types in human or animal skin:
The technique is used in different types of studies:
- Allergic or allergy like adverse effects of drugs (observed or potential)
- Anti-allergic effects of new drugs (administration: intradermal injection (ID), intra probe drug delivery (IPD) or topical).
- Mechanisms in allergic-inflammatory reactions (Type I allergy, Chronic urticaria & autoimmune reactions)
In vitro release of biomarkers from human blood/other cells (HBR) or animal blood/other cells (ABR):
- Allergic or allergy like adverse effects of drugs (observed or potential)
- Anti-allergic effects of new drugs
- Detection of biological activity of allergens
- Identification of allergens in food
- Monitoring effect of immunotherapy or other treatment
- Diagnostic, clinical study