Are you a healthcare professional?
Service Laboratory
We support clinicians in the diagnosis of allergy and chronic spontaneous urticaria (CSU) using our basophil histamine release assay (BHRA). Our services are used by hospitals, allergy/immunology specialists, and private companies.
We offer two variants of the BHRA:
- Allergen-induced BHRA (a-BHRA) for diagnosing patients with allergy. This assay is also known as the HR-Test.
- Serum-induced BHRA (s-BHRA) for diagnosing patients with CSU. This assay is also known as the HR-Urticaria Test.
Are you a biotech or pharmaceutical company?
Contract Research
RefLab offers contract research services based on our human ex vivo skin model and basophil histamine release assay (BHRA).
Together, these highly translational human models enable prediction of first-in-human immune and adverse immune responses, including pseudo-allergic reactions, for new therapeutics.
We support investigations across areas such as dermal drug delivery, hypersensitivity reactions, and local metabolism. Each study is tailored to meet the scientific and regulatory requirements of your project.
About RefLab
RefLab is a private laboratory specializing in the identification of specific allergens suspected of eliciting allergic symptoms, as well as autoantibodies directed against IgE and the IgE receptor in patients with chronic spontaneous urticaria (CSU).
We also operate as a contract research organization (CRO), offering biological standardization of allergens and human ex vivo models to investigate allergic side effects of new therapeutics, as well as dermal drug delivery, local pharmacodynamic effects, and local metabolism in the preclinical phase.
Learn more about our CRO activities here.
